1152-202 Neurohormonal activation in children with heart failure due to a congenital heart defect
نویسندگان
چکیده
منابع مشابه
Neurohormonal activation and the chronic heart failure syndrome in adults with congenital heart disease.
BACKGROUND Neurohormonal activation characterizes chronic heart failure, relates to outcome, and is a therapeutic target. It is not known whether a similar pattern of neurohormonal activation exists in adults with congenital heart disease and, if so, whether it relates to common measures of disease severity or whether cardiac anatomy is a better discriminant. METHODS AND RESULTS Concentration...
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Background Heart failure (HF) in infants and children with congenital heart disease (CHD) is a crucial complication with different outcomes. Many biomarkers are used as prognostic indicators. Soluble ST2 (sST2) is one of these markers studied in adults with HF. We aimed to study the prognostic value of sST2 in CHD children with HF. Materials and Methods In current case-control study, thirty-six...
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A ccording to the neurohormonal model, heart failure is a syndrome that develops because an initial heart injury activates endogenous neurohormonal systems that exert a deleterious effect to the myocardium and on the circulation. This new model regards heart failure primarily as a neurohormonal disorder with main pathophysiologic abnormality the activation of various neurohormonal systems. Arte...
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Introduction: With respect to high association of skeletal chest deformity with cardiac abnormalities, these patients should be evaluated for evidence of cardiac involvement. So, we used echocardiography to investigate this association. Methods: This case-control study was done on 144 patients with skeletal chest deformity referred to OPD clinic. 240 persons were selected as control group, with...
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Rev Esp Cardiol 2004;57(4):347-56 347 Chronic heart failure secondary to ventricular dysfunction is characterized by neurohormonal activation, reflected mainly as increased sympathetic and reninangiotensin system activation. Increased plasma levels of several neurohormones have been associated with increased morbidity and mortality. Neurohormone activation is part of the mechanism of compensati...
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2004
ISSN: 0735-1097
DOI: 10.1016/s0735-1097(04)91656-7